CompleteFeb 26, 2025 – Aug 26, 2025

Microplastics Reduction Trial I

Detoxification Research

Experiment Overview

Single-intervention N=1 testing high-dose phospholipids (BodyBio PC) on circulating microplastic particles in serum. By month 4, total particles fell from 42 → 14 (-66.7%). At month 6, levels rebounded to 34 (+142.9% vs. month 4), likely from identifiable new exposures.

Protocol

11 fl oz (2 tablespoons) BodyBio PC daily
21 tablespoon with breakfast
31 tablespoon with dinner
4Maintained all other lifestyle factors constant (bedding, clothing, containers, diet, routine)
5No other new interventions during months 0–4

Note: New exposures identified in months 4–6. Core protocol above was held constant during months 0–4.

Baseline → Month 4

-66.7%

42 → 14 particles

Month 4 → Month 6

+142.9%

14 → 34 particles

Final vs. Baseline

-19.0%

42 → 34 particles

Microplastic Particles Over Time

Metric:

% Change by Particle Size

Range:

Baseline → Month 6 (Aug 2025)

<10 μm

+47.4%

increase

10–30 μm

-66.7%

reduction

30–70 μm

-100%

reduction

Conclusions

High-dose phospholipid supplementation was associated with a large early decline in circulating microplastic particles (≈-66.7% by month 4), followed by a rebound coincident with new exposures. Final levels remained below baseline (-19.0%).

Interpretation: phospholipids plausibly act via membrane repair/turnover and bile production/flow; environmental inflow remains a dominant variable.

A much larger reduction should be achievable combining interventions (e.g. environmental overhaul, reverse osmosis water, etc.) instead of isolating a single intervention (high dose phospholipids).

Read the X thread for more context

Study Details

Subject

N=1 (self)

Duration

6 months (baseline + every 2 months)

Assay

Fluorescent microscopy (Blueprint Biomarkers)

Primary endpoint

Total particle count (serum)

Secondary

Size buckets: <10 μm, 10–30 μm, 30–70 μm

Limitations

Single-subject, no control group.
Environmental inflow is hard to fully constrain.
Small blood sample (100 µL).
Serum measurement only; doesn't measure tissue burden.
Size window limited to <70 µm; nano-range not captured.
Test only has one third party validation (PDF).

Files

Percentile values in reports are auto-generated and incorrect except for the August, 2025 report. April report collection date is also incorrect (should be 2025-04-26).

Tests

3rd Party Assay AttestationDownload →
February, 2025 Lab ReportDownload →
April, 2025 Lab ReportDownload →
June, 2025 Lab ReportDownload →
August, 2025 Lab ReportDownload →

Other

Microplastics X Thread @daviddorg (PDF)Download →

Materials & Expenses

Testing

Blueprint Microplastics Blood Test

4 tests × $135 each

View product →

$540.00

Supplements

BodyBio PC (Phospholipid Complex)

12 × 16 oz bottles × $199.99 each